TABLE 1.
Demographic Characteristics of Participants in a Multimodal Neuroimaging Study of Premenstrual Dysphoric Disorder (PMDD)a
| Characteristic | PMDD Patients | Comparison Subjects | ||
|---|---|---|---|---|
| Age (years) | Mean | SD | Mean | SD |
| PET | 37.3 | 7.8 | 36.5 | 8.5 |
| fMRI | 38.1 | 8.2 | 36.0 | 8.0 |
| Body mass index (kg/m2) | ||||
| PET | 27.4 | 5.3 | 25.7 | 4.9 |
| fMRI | 27.4 | 5.4 | 24.6 | 4.8 |
| Education (years) | ||||
| PET | 15.8 | 1.6 | 15.5 | 1.5 |
| fMRI | 15.7 | 2.3 | 16.0 | 1.8 |
| Global Assessment of Functioning Scale scores | ||||
| PET | 62.9 | 6.5 | 91.0 | 1.7 |
| fMRI | 62.9 | 6.3 | 92.0 | 2.9 |
| Age at onset (years) | ||||
| PET | 27.0 | 11.3 | ||
| fMRI | 25.4 | 11.4 | ||
| Duration (years) | ||||
| PET | 10.3 | 8.3 | ||
| fMRI | 12.7 | 9.3 | ||
| Menses-related change in negative affectb | ||||
| PET | 43.0 | 10.0 | ||
| fMRI | 42.7 | 11.3 | ||
|
| ||||
| N | N | |||
|
| ||||
| Race | ||||
| PET | 6 black, 9 white | 6 black, 9 white | ||
| fMRI | 7 black, 1 Asian, 6 white | 4 black, 1 Asian, 9 white | ||
| Handedness | ||||
| PET | 15 right | 15 right | ||
| fMRI | 14 right | 12 right, 2 left | ||
a
Overlap of participants in PET and fMRI studies: four women with PMDD and eight comparison subjects in the PET-only group; three women with PMDD and seven comparison subjects in the fMRI-only group; 11 women with PMDD and seven comparison subjects participated in both PET and fMRI scanning.
b
Average change in negative affect as measured by the visual analogue scale from 7 days before the onset of menses to 7 days after the end of menses during three baseline screening menstrual cycles.