. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: Neurobiol Dis. 2013 Oct 8;62:172–178. doi: 10.1016/j.nbd.2013.09.019

Table 1.

Iron-related Genes Investigated

Gene id	Location	Symbol	Gene Name
391059	1p21.2	FRRS1	ferric-chelate reductase 1
			function: ferric reductase
148738	1q21.1	HFE2	hemochromatosis type 2
			function: hepcidin regulation
30061	2q32	SLC40A1	solute carrier family 40, member 1
			function: iron export from cells
4057	3p21.31	LTF	lactotransferrin
			function: iron binding and transport
7018	3q22.1	TF	transferrin
			function: iron binding and transport
1356	3q23-q25	CP	ceruloplasmin
			function: peroxidation of Fe²⁺transferrin to Fe³⁺ transferrin
7037	3q29	TFRC	transferrin receptor
			function: transferrin endocytosis and recycling
94033	5q21.3	FTMT	mitochondrial ferritin
			function: iron binding and oxidation
3077	6p21.3	HFE	hemochromatosis
			function: regulate iron absorption
7036	7q22	TFR2	transferrin receptor 2
			function: mediates cellular uptake of transferrin-bound iron
4891	12q13	SLC11A2	solute carrier family 11, member 2
			function: iron absorption and transport of divalent metals
3658	15q25.1	IREB2	iron-responsive element binding protein 2
			function: protein regulation via iron-responsive elements
1534	17q23.3	CYB561	cytochrome b561
			function: ferric reductase
2235	18q21.3	FECH	ferrochelatase
			function: catalyze the insertion of iron into heme
57817	19q13.1	HAMP	hepcidin antimicrobial peptide
			function: regulation of iron storage
9843	Xq11-q12	HEPH	hephaestin
			function: iron transport