Table 3.
The pathways most enriched as found by KEGG
| Pathway ID | Pathway name | Selection counts2006 | Count2006 | Enrichment2008 |
|---|---|---|---|---|
| Down-regulated pathways | ||||
| hsa03030 | DNA replication | 27 | 36 | 22.19064 |
| has04110 | Cell cycle | 48 | 124 | 21.17736 |
| hsa03460 | Fanconi anaemia pathway | 30 | 52 | 19.51810 |
| hsa03430 | Mismatch repair | 14 | 23 | 9.794446 |
| hsa03440 | Homologous recombination | 15 | 28 | 9.372881 |
| hsa00240 | Pyrimidine metabolism | 25 | 101 | 6.649322 |
| hsa03410 | Base excision repair | 13 | 33 | 6.200618 |
| hsa03420 | Nucleotide excision repair | 15 | 46 | 5.828512 |
| hsa04114 | Oocyte meiosis | 24 | 112 | 5.205605 |
| hsa00230 | Purine metabolism | 30 | 166 | 4.769290 |
| hsa05166 | Human T lymphocyte virus type 1 infection | 38 | 263 | 3.634506 |
| hsa04115 | p53 signalling pathway | 15 | 68 | 3.609288 |
| hsa00670 | One carbon pool by folate | 7 | 19 | 3.355224 |
| hsa05222 | Small cell lung cancer | 17 | 87 | 3.345462 |
| hsa05200 | Pathways in cancer | 43 | 328 | 3.107403 |
| hsa00900 | Terpenoid backbone biosynthesis | 7 | 21 | 3.053525 |
| hsa04914 | Progesterone-mediated oocyte maturation | 16 | 86 | 2.938970 |
| hsa03013 | RNA transport | 24 | 157 | 2.824326 |
The count of the DE genes' entities directly associated with the listed Pathway ID.
The count of the chosen background population genes' entities associated with the listed pathway ID.
The enrichment score value of the pathway ID, it equals ‘–log10(P-value)’.