Figure 3.

RER (A–D) is selectively reduced by telmisartan (T), but not by amlodipine (A) or the combination telmisartan + amlodipine (T + A). E–H: VO₂ did not differ between groups. I–L: cumulative energy intake was reduced in C_chow, but remained unchanged in telmisartan-, amlodipine- and telmisartan + amlodipine-treated rats. M–P: The locomotion of rats was increased during the dark period when fed with CD, but was not influenced compared with C_CD by any drug treatment. RER, energy intake and locomotion are depicted only at the third day of measurements. The gray bars indicate the dark periods. Means ± SEM, n = 11–12, *P < 0.05 versus C_CD.