Table 2. Cyclization of Aryl and Heteroaryl Enones with the Heterogeneous Gold Catalyst [Au]a.
Reaction conditions: AuCl3 (1 mol %)/AgSbF6 (2 mol %), premixed prior to reaction, CH2Cl2 or toluene, rt unless otherwise indicated, minimal light conditions.
Reactions monitored using thin layer chromatography.
Isolated yields.
Reactions at 80 °C.
Reaction at 60 °C.
10 mol % catalyst. PMP = para-methoxyphenyl, TMS = trimethylsilyl, TMP = 2,4,6-trimethoxyphenyl.