Table 4. Conversion of Benzoxazine Intermediate 12 to Diverse Heterocycles with Bis-Nucleophiles.

bis-nucleophile	product	yield (%)
2-aminophenol	1	87
2-amino-4-chlorophenol	14	63
1,2-diaminobenzene	15	98
2-aminothiophenol	16	93
cysteamine	17	44