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. 2014 Mar 1;88(1):106–118. doi: 10.1016/j.bcp.2013.12.026

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© 2014 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig. 7 — Schematic overview of postulated transport systems (T1, T2, T3) for E17βG, E3S, and TC in ER vesicles.

Transport and inhibitory effect (⊥) of the different compounds are indicated by the different colors used. E, estradiol; E17βG, estradiol-17β-glucuronide; E3S, estrone-3-sulfate; TC, taurocholate; UDP-GA, UDP-glucuronic acid; CYPs, cytochrome P450s; UGTs, UDP-glucuronosyltransferases, STS, steroidsulfatase.