Table 3.

Transcription factor classification via enrichment analysis for the whole gene set. Result of gene set enrichment analysis (GSEA) for all genes with FC values ranging from 177 to 0.045, including those with unchanged expression values (FC: 2–0.5) as well. Functional groups referred to as transcription factor classes were identified to be overrepresented (+1 ⩾ “score” > 0) or underrepresented (−1 ⩽ “score” < 0) according to their FC-dependent ranking.

Factor class description	Hits	Score	p-Value
AP-1 (-like) components	ATF3, FOSL2, JUN	0.9037	9.66E−04
Basic domains	n/a	0.4760	2.90E−02
Leucine zipper factors (bZIP)	n/a	0.4165	9.48E−02
Homeo domain only	n/a	−0.5699	4.85E−02