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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: J Med Chem. 2012 Oct 26;55(22):10160–10176. doi: 10.1021/jm3012728

Table 1.

Affinity of 13 for S. aureus, E. coli, and E. faecalis FtsZ at 25 °Ca

FtsZ Kd (μM)
S. aureus 3.5 ± 0.5
E. coli 3.8 ± 0.3
E. faecalis 21.8 ± 4.6
a

Solution conditions were 50 mM Tris·HCl (pH 7.4), 50 mM KCl, and 2 mM magnesium acetate.