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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: J Med Chem. 2012 Oct 26;55(22):10160–10176. doi: 10.1021/jm3012728

Table 5.

Activity of 13 against Other Gram-Positive and Gram-Negative Bacteria

bacterial strain ATCC no. MIC (μg/mL)
S. pyogenes (Strep A) 19615 2.0
S. agalactiae (Strep B) 12386 16.0
B. subtilis 23857 4.0
A. baumannii 19606 16.0
K. pneumoniae 13883 32.0
K. pneumoniae (ESBL)a 700603 16.0
a

ATCC 700603 is an ESBL-producing strain of K. pneumoniae that expresses the SHV-18 lactamase.