Table 3.
Results of the overall volumes meta-analyses.
| Volume | aStudies | bGroups | N (Fc) | Analysis type | Q | I2 | Outcome | Cohen's d | Percentage difference | dMean difference | CI 95% | p-Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ICV | 77 | 100 | 14,957 (48%) | FFX | 62.3 | 0 | M > F | 3.03 | 12% | 135.3 | 117.8–152.8 | <10−6 |
| TBV | 31 | 40 | 2532 (50%) | RFX | 92.8 | 57.9 | M > F | 2.1 | 10.8% | 131 | 92.1–170.0 | <10−6 |
| Cb | 22 | 24 | 1851 (54%) | FFX | 12.5 | 0 | M > F | 3.35 | 9.8% | 51.06 | 38.7–63.5 | <10−6 |
| GM | 60 | 71 | 7934 (52%) | FFX | 26.5 | 0 | M > F | 2.13 | 9.4% | 56.51 | 44.2–68.9 | <10−6 |
| WM | 57 | 69 | 7515 (52%) | FFX | 39.9 | 0 | M > F | 2.06 | 12.9% | 44.4 | 34.2–54.6 | <10−6 |
| CSF | 35 | 45 | 4484 (50%) | FFX | 15.5 | 0 | M > F | 1.21 | 11.5% | 18.72 | 9.6–27.8 | 3.2 × 10−5* |
| Cbl | 19 | 26 | 1842 (51%) | FFX | 9.7 | 0 | M > F | 1.68 | 8.6% | 7.78 | 4.2–11.4 | 1.4 × 10−5* |
Abbreviations: Cb, cerebrum; Cbl, cerebellum; CSF, cerebrospinal fluid; F, females; FFX, fixed effects model; GM, grey matter; I2, I2 index; ICV, intracranial volume; N, number of subjects; Q, Cochran's Q test; RFX, random effects model; TBV, total brain volume; WM, white matter.
a
Number of studies reporting the respective volumes.
b
Number of age-matched gender groups in the analysis (some studies provide more than one sample).
c
Number of females in percentages.
d
Values reported in mL.