Fig. 5.

Median methylation of (a) HPV18, (b) HPV31 and (c) HPV33 L2 and L1 in CIN2+ group in single infections (white bar) vs. multiple infections (black bar). A patient was considered to have multiple infection if positive for any of the 15 HR-HPV types. Out of 77 HPV18 positive CIN2+, 14 were single infections and 63 multiple. For HPV31, there were 37 single and 62 multiple infections. HPV33 infected CIN2+ consisted of 21 single and 53 multiple infections. Unadjusted p-values (*) were plotted on the right Y-axis.