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. 2014 Mar 28;9(3):e93462. doi: 10.1371/journal.pone.0093462

Table 2. Gene ontology classification into biological process of all genes significantly (p<0.05) differentially expressed in response to 1 mM and 100 pM melatonin.

1 mM Melatonin 100 pM Melatonin
GO Slim ID Biological Process up-regulated down-regulated up-regulated down-regulated
GO:0009987 cellular process 57.73 57.40 43.33 55.32
GO:0008152 metabolic process 50.72 51.59 50.00 53.19
GO:0006950 response to stress 42.27 16.74 30.00 29.79
GO:0009058 biosynthetic process 28.60 35.82 23.33 31.91
GO:0009719 response to endogenous stimulus 25.00 9.13 23.33 12.77
GO:0009607 response to biotic stimulus 23.92 6.64 13.33 14.89
GO:0007154 cell communication 23.56 8.85 6.67 14.89
GO:0006810 transport 23.20 14.38 10.00 12.77
GO:0007165 signal transduction 21.94 6.50 3.33 10.64
GO:0009628 response to abiotic stimulus 21.76 17.43 23.33 17.02
GO:0008150 Biological process * 18.88 23.79 23.33 21.28
GO:0016043 cellular component organization 15.65 17.15 3.33 17.02
GO:0019538 protein metabolic process 12.59 11.62 3.33 19.15
GO:0009056 catabolic process 12.05 10.79 20.00 6.38
GO:0007275 multicellular organismal development 11.87 17.29 10.00 12.77
GO:0008219 cell death 10.61 1.94 3.33 8.51
GO:0019748 secondary metabolic process 8.99 7.61 10.00 4.26
GO:0006139 nucleobase-containing compound metabolic process 8.45 22.13 13.33 14.89
GO:0006464 cellular protein modification process 7.37 7.05 0 10.64
GO:0009605 response to external stimulus 6.83 4.01 3.33 6.38
GO:0006629 lipid metabolic process 5.58 9.68 13.33 8.51
GO:0000003 reproduction 4.86 5.39 0 4.26
GO:0009791 post-embryonic development 4.86 9.68 3.33 4.26
GO:0005975 carbohydrate metabolic process 4.32 13.69 3.33 4.26
GO:0009653 anatomical structure morphogenesis 4.14 10.93 3.33 4.26
GO:0009991 response to extracellular stimulus 3.60 1.94 3.33 6.38
GO:0040007 growth 3.60 5.81 0 4.26
GO:0016049 cell growth 2.70 3.46 0 2.13
GO:0030154 cell differentiation 2.34 5.39 3.33 2.13
GO:0019725 cellular homeostasis 1.98 2.49 3.33 0
GO:0006091 generation of precursor metabolites and energy 1.62 8.16 3.33 0
GO:0009908 flower development 1.62 3.04 0.00 4.26
GO:0009790 embryo development 1.26 1.52 0.00 2.13
GO:0015979 photosynthesis 1.26 9.68 6.67 2.13
GO:0007049 cell cycle 1.08 1.80 0 2.13
GO:0006259 DNA metabolic process 0.90 2.21 0 0
GO:0009838 abscission 0.54 0.14 0 2.13
GO:0009856 pollination 0.54 0.41 0 0
GO:0040029 regulation of gene expression, epigenetic 0.36 1.11 0 2.13
GO:0006412 translation 0.18 1.80 0 4.26
GO:0009606 tropism 0.18 0.69 0 0
GO:0007267 cell-cell signaling 0 0.28 0 0
GO:0009875 pollen-pistil interaction 0 0.14 0 0

Genes were classified using AmiGO GO slimmer. The proportion of genes assigned to each category was calculated by dividing the number of genes assigned to a category by the total number of differentially expressed genes for each treatment. Genes may be classified into one or more GO Slim Term.

*Indicates biological process is unknown.