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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: Mol Cancer Ther. 2012 Aug 29;11(11):2362–2372. doi: 10.1158/1535-7163.MCT-12-0107

Figure 1.

Figure 1

Overall survival and E-cadh expression in human lung cancer patients with cigarette smoking status. (A) Kaplan-Meier survival curve for overall survival of lung cancer patients with never-smokers versus current smokers or former smokers. (B) Expression of E-cadh in human lung cancers by IHC analyses of TMAs that contain normal and tumor tissues from patients, either current or former smokers, with adeno and squamous cell carcinoma. Representative of E-cadh staining in one specimen from each group was shown. (C) TMA was stained for E-cadh and the index score was calculated as described in Materials and Methods. (D) Effect of pack-years of cigarette smoking on the expression of E-cadh in adeno and squamous cell carcinoma patients with smoking status. Red color indicates strong and blue color indicates weak E-cadh expression. *p<0.05; ***p<0.001. (E) Kaplan-Meier survival curve for overall survival of lung cancer patients according to staining for E-cadh.