Table 2.

Sizes and zeta potentials of LNCs transacylated with 1.2 mg/mL of chitosan/anti-EGFR siRNA complexes

Formulation	Size (nm)	Polydispersity index	Zeta potential (mv)
LNC 50 nm + 1.2 mg/mL chitosan + 10 nM anti-EGFR siRNA	94.9±3.9	0.25	19.2±0.6
LNC 50 nm + 1.2 mg/mL chitosan + 20 nM anti-EGFR siRNA	93.7±0.8	0.23	18.9± 1.1
LNC 50 nm + 1.2 mg/mL chitosan + 30 nM anti-EGFR siRNA	95.5±4.1	0.24	17.5±0.4
LNC 50 nm + 1.2 mg/mL chitosan + 40 nM anti-EGFR siRNA	96.4±1.0	0.23	15.2±0.9

Note:

Data are shown as mean ± standard error of the mean (n=3).

Abbreviations: LNC, lipid nanocapsules; anti-EGFR, anti-epidermal growth factor receptor; siRNA, small interfering ribonucleic acid.