Figure 6. Histological changes (TUNEL assay) in the liver of mice subjected to restrain stress and treatment with prazosin and yohimbine followed by exposure to restraint stress.

In the demonstration of apoptosis in situ by the TUNEL assay, TUNEL positive hepatocytes are marked by black arrows (A), and are expressed as apoptotic index (B), ** p<0.01 compared with control animals. RS: restraint stress. Magnification×400.