Figure 7. Small animal PET imaging and quantification.
Decay-corrected whole-body PET images were acquired at different time points. (A) PET images of S180 fibrosarcoma-bearing mouse static scans at 0.5, 1, 1.5, and 2 h after the injection of [18F]FPGLU. The same S180 fibrosarcoma-bearing mouse static scan at 1 h after injection of [18F]FDG. (The red arrows indicate the tumor.) (B) PET images of SPCA-1 or LTEP-a-2 human lung adenocarcinoma-bearing nude mouse static scans at 1 h after the injection of [18F]FPGLU or [18F]FDG. (The red arrows indicate the tumor.) (C) A comparison of tumor uptake of [18F]FPGLU and [18F]FDG in S180 fibrosarcoma, LTEP-a-2, and SPCA-1 human lung adenocarcinoma at 1 h after injection. (n = 3 per group; bars represent means ± SD.).
