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Quinpirole-induced locomotor activity in 12 10-min blocks (a) and in the 120 min test period (b) of rats pretreated with risperidone (1.0 mg/kg) or VEH followed by PCP (3.2 mg/kg, sc) for 5 days in adolescence. All rats were injected with quinpirole (1.0 mg/kg, sc) and then measured for motor activity for 120 min. Data are expressed as mean + SEM.
