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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Chromosoma. 2013 Oct 15;123(0):43–55. doi: 10.1007/s00412-013-0439-4

Figure 4. Centromere pairing in mouse.

Figure 4

Both exchange and non-exchange chromosomes undergo centromere pairing in mouse spermatocytes. A) Chromosome spreads of mouse spermatocytes in late meiotic prophase I stained with antibodies against the central element of the synaptonemal complex SYCP1 and the lateral element SYCP3. The spread contains several desynapsed chromosome pairs in which the SYCP1 has largely disassembled, but with persisting blocks of SYCP1 at the centromeres (one end of the telocentric chromosome) and also at the chiasmata. B) Large images of an exchange and a non-exchange chromosome pair from the spread shown in panel A, with schematic diagrams. Figure 5. Model for centromere pairing and rotational freedom.