Table III.

Effect of Nexrutine intervention on inflammation, fibrosis in BK5-Cox-2 mice.

Treatment	Animal ID#	Inflammation	Fibrosis	mPan 1A	mPan 1B	mPan 2	mPan 3
Control	PK12 100	0	0
Control	PK12 103	0	0
Control	PK12 104	0	0
Control	PK12 117	0	0
Control	PK12 125	0	0
Control	PK12 101	0.5+	0.5+
Control	PK12 102	0.5+	0.5+		FOCAL
Control	PK12 116	0.5+	0.5+	Y
Control	PK12 123	0.5+	0.5+
Control	PK12 124	0	0.5+
Control	PK12 126	0	0.5+
Control	PK12 127	0.5	0.5+
Control	PK12 128	0.5+	0.5+
Control	PK12 114	0	0.5A
Control	PK12 62	1+	1+
Control	PK12 63	1+	1+
Control	PK12 64	1+	1+
Control	PK12 80	1+	1+
Control	PK12 115	0.5+	1+	FOCAL
Control	PK12 66	2+	2+		Y
Control	PK12 78	1+	2+			Y
Control	PK12 91	0.5+	2+
Control	PK12 99	1+	2+			Y
Nx	PK12 86	0	0
Nx	PK12 90	0	0
Nx	PK12 119	0	0
Nx	PK12 121	0	0
Nx	PK12 129	0	0
Nx	PK12 72	0.5+	0.5+
Nx	PK12 73	0.5+	0.5+
Nx	PK12 83	0	0.5+
Nx	PK12 84	0.5+	0.5+
Nx	PK12 88	0.5+	0.5+		Y
Nx	PK12 89	0.5+	0.5+
Nx	PK12 118	0.5+	0.5+	FOCAL
Nx	PK12 120	0	0.5+
Nx	PK12 122	0.5	0.5+
Nx	PK12 130	0.5+	0.5+
Nx	PK12 131	0	0.5+
Nx	PK12 74	1+	1+
Nx	PK12 77	1+	1+
Nx	PK12 85	0.5+	1+			Y
Nx	PK12 87	1+	1+			Y
Nx	PK12 133	1+	1+		Y
Nx	PK12 79	1+	2+			Y
Nx	PK12 132	3+	3+		Y