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. 2014 Apr;5(1):28–37. doi: 10.1055/s-0034-1368670

Table 1. Characteristics of studies comparing LLIF/XLIF/DLIF with PLIF/TLIF for lumbar degenerative disease.

Investigator (y)
Study design
CoE
Population Condition LLIF/XLIF/DLIF PLIF/TLIF Follow-up (% followed)
Deluzio et al (2010)
Retrospective cohort (using historical cohort from same institution)
CoE: III
N = 211
• Age (mean): 55.5 y
• Male: 65%
• Degenerative spine conditions (details NR)
• Symptom duration: NR
• XLIF from L1–L2 to L4–L5 and MIS TLIF/transsacral fusion at L5-S1
• Type of graft: NR
n = 109
• Number of levels: 2
• 2006–2009
• Open PLIF (historical cohort)
• Type of graft: NR
n = 102
• Number of levels: 2
• Prior to 2006
Follow-up period NR (% NR)
Rodgers et al (2010)
Retrospective cohort (using historical cohort from same institution)
CoE: III
N = 60
• Age (mean): 83.4 y
• Male: 42%
• Degenerative spine conditions (stenosis, spondylolisthesis, scoliosis, postlaminectomy
• Symptom duration: NR
• XLIF with unilateral or bilateral pedicle screws, percutaneous (n = 39)
• Type of graft: composite of demineralized bone matrix, cancellous allograft, local bone source, and bone marrow aspirate
n = 40
• 1-level (n = 25), 2-level (n = 7), 3-level (n = 8): mean 1.6 levels from L1-L5 (62.5% including L4–L5)
• Open PLIF (historical cohort) with unilateral or bilateral pedicle screws, open exposure
• Type of graft: composite of demineralized bone matrix, cancellous allograft, local bone source, and bone marrow aspirate
n = 20
• 1-level (n = 4), 2-level (n = 7), 3-level (n = 7), 5-level (n = 1), 7-level (n = 1): mean 2.6 levels from T10-S1 (80.0% including L4–L5)
≥ 3 mo (% NR)
Knight et al (2009)
Retrospective cohort (using historical cohort from senior author's practice)
CoE: III
N = 98
• Age (mean): 61 y
• Male: % NR
• Degenerative spine conditions (details NR)
• Symptom duration: NR
• XLIF or DLIF
• Type of graft: NR
n = 58
• 1-level (n = 38), 2-level (n = 19), 3-level (n = 1): from T12-L5
• 2004–2006
• Open PLIF (historical cohort)
• Type of graft: NR
N = 40
• Number of levels: NR, excluded L5-S1
• 1992–1998
XLIF or DLIF: 15 mo (3–34 mo) (% NR)
PLIF: follow-up period NR (% NR)

Abbreviations: CoE, class of evidence; DLIF, direct lateral interbody fusion; f/u, follow-up; LLIF, lumbar lateral interbody fusion; MIS, minimally invasive surgical techniques; NR, not reported; PLIF, posterior lateral interbody fusion; TLIF, transforaminal lumbar interbody fusion; XLIF, extreme lateral interbody fusion.