Figure 1.

Trajectory of eGFRcys^a decline^b by age and BMI^a category

^a eGFRcys=cystatin C estimated glomerular filtration rate, ml/min/1.73m², BMI= body mass index, kg/m²

^bAdjusted for baseline age, race, sex, hyperlipidemia, smoking status, and physical activity.

*Difference in eGFRcys slope BMI 25.0–29.9 vs. BMI 18.5–24.9, p=0.01

**Difference in eGFRcys slope BMI 25.0–29.9 vs. BMI 18.5–24.9, p=0.002

◆Difference in eGFRcys slope BMI ≥40 vs. BMI 18.5–24.9, p=0.02

◆◆Difference in eGFRcys slope BMI 30.0–39.9 vs. BMI 18.5–24.9, p=0.002