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Cytotoxicity Profile (IC50 values) of Non-Ionic Surfactants in Caco-2 cells after incubation for 4 h at 37°C
| Excipient | IC50 values of Excipients (%, v/v) | IC50 values of Excipients and Metformin HCL (10 mM) (%, v/v) |
|---|---|---|
| Tween-20 | 4.90 ± 0.02 | 2.50 ± 0.32 |
| Labrasol | 0.22 ± 0.01 | 0.24 ± 0.05 |
| Transcutol-P | 2.04 ± 0.35 | 1.84 ± 0.36 |
| Lauroglycol-90 | >1 | >1 |
| Maisine 35-1 | >1 | >1 |
| Peceol | >1 | >1 |
