Table I.
Formulations | Content (% w/w) | Klucel LF/Eudragit RL PO ratios | Mechanical properties | |||
---|---|---|---|---|---|---|
Klucel LF | Eudragit RL PO | Triethyl citrate | Tensile strength (Newton/mm2) | % Elongation at break | ||
5%E-T1 | 0 | 5 | 1 | –a | 1.57 ± 0.35 | 31.03 ± 7.58 |
8%E-T1 | 0 | 8 | 1 | –a | 3.72 ± 0.44 | 134.23 ± 13.33 |
11%E-T1 | 0 | 11 | 1 | –a | 5.23 ± 0.32 | 197.58 ± 22.76 |
5%K-T1 | 5 | 0 | 1 | –a | 0.65 ± 0.02 | 17.54 ± 1.22 |
8%K-T1 | 8 | 0 | 1 | –a | 2.89 ± 0.30 | 50.34 ± 6.59 |
11%K-T1 | 11 | 0 | 1 | –a | 3.98 ± 0.15 | 65.83 ± 5.76 |
8%K1-E1-T1 | 4 | 4 | 1 | 1:1 | 2.43 ± 0.21 | 19.24 ± 4.48 |
8%K3-E1-T1 | 6 | 2 | 1 | 3:1 | 3.89 ± 0.40 | 53.10 ± 5.48 |
8%K5-E1-T1 | 6.67 | 1.33 | 1 | 5:1 | 8.84 ± 0.18 | 72.09 ± 2.30 |
8%K5-E1-T0 | 6.67 | 1.33 | 0 | 5:1 | 20.24 ± 1.85 | 8.76 ± 4.91 |
8%K5-E1-T2 | 6.67 | 1.33 | 2 | 5:1 | 2.17 ± 0.34 | 124.54 ± 27.46 |
11%K1-E1-T1 | 5.5 | 5.5 | 1 | 1:1 | 4.49 ± 0.09 | 17.10 ± 2.97 |
11%K3-E1-T1 | 8.25 | 2.75 | 1 | 3:1 | 7.79 ± 0.89 | 27.65 ± 3.16 |
11%K5-E1-T1 | 9.17 | 1.93 | 1 | 5:1 | 11.47 ± 0.32 | 47.81 ± 1.27 |
aFormulation contained only one polymer