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. 2014 Jan 16;15(2):388–399. doi: 10.1208/s12249-014-0073-3

Table III.

Optimization of Drug Loading in Various Nanocarriers

Carrier system Process variable Average particle size (nm) (mean±S.D. n = 3) % Entrapment efficiency (mean±S.D. n = 3)
Liposomes Mole % of drug with respect to lipid
4 160 ± 2.2 37.5 ± 1.7
5 179 ± 1.7 38.2 ± 1.9
6 185 ± 2.4 49.2 ± 1.5
7 181 ± 1.2 44.72 ± 1.2
Nanoparticles Drug/polymer ratio (%w/w)
1 170 ± 1.5 28.35 ± 2.7
2 178 ± 1.4 62.34 ± 1.5
3 175 ± 1.7 41.45 ± 1.1
4 182 ± 2.6 35.76 ± 1.3
Dendrimers Dendrimer/drug ratio
1:6 8 ± 0.26 25.54 ± 0.35
1:7 8 ± 0.39 26.12 ± 0.51
1:8 8 ± 0.271 28.26 ± 0.74
1:9 8 ± 0.24 27.34 ± 0.42
1:10 8 ± 0.12 26.25 ± 0.34
Carbon nanotubes Carboxylated MWCNTs/drug ratio
1:1 210 ± 0.52 54.57 ± 1.1
1:2 215 ± 0.20 61.54 ± 0.9
1:3 213 ± 0.19 74.70 ± 1.9
1:4 212 ± 0.52 71.68 ± 1.3

Results are represented as mean±SD, n = 3