Figure 2.

Human immunodeficiency virus (HIV) infection interrupts coregulation of cytokine networks in (A) blood and (B) semen. Depicted is a table divided diagonally between HIV-uninfected (top right) and HIV-infected (bottom left) with shading representing the R² valuesof correlations between all cytokines and chemokines assayed. Each rectangle represents an R² value indicative of the level of correlation between each cytokine or chemokine assayed. R² values < 0.20 = white rectangles; ≥0.2 to <0.4 = gray rectangles; ≥0.4 = black rectangles. Abbreviations: G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte macrophage colony-stimulating factor; HIV, human immunodeficiency virus; IFN, interferon; IL, interleukin; MCP, monocyte chemotactic protein; MIP, macrophage inflammatory protein; RANTES, regulated upon activation normal T cell expressed and secreted; TNF, tumor necrosis factor.