Table 2.
Sequence Varianta | Subjects (N)b |
---|---|
G629S | 4 |
I341T | 3 |
(F718L)c | 3 |
A269V, P375L, L394F, (H446Y), A472V, K519R, A614V, Q639H, P656S | 2 |
G201E, S212F, (R264G), A285S, (V327G), Q323H, A336T, V337M, (N345S)d, K426R, V450G, H465Y, A473V, (V483A), P617S, P628A, V634A, Q651E, G653S, (S660N), R800C, (G822D)c, (M828V)c, R847H, N855D, H863R, T892I, (E903G)c, (G920S), V927M, S1000L, D1005N, (R1006C)d | 1 |
a Variants in parentheses were detected only as mixtures with wild type. Variants in italics are at conserved residues. Variants in bold were selected for phenotyping.
b Number of subjects noted to have each listed mutation. At least 1 subject per mutation had no history of prior anti-cytomegalovirus therapy.
c Not found on resequencing of any of the involved specimens.
d Mixture confirmed on resequencing of the involved specimen.