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. 2014 Mar;133(3):729–738.e18. doi: 10.1016/j.jaci.2013.09.039

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© 2013 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig E3 — Fractal analysis of the segmented airway tree with FracLac (ImageJ) software. The JPEG image (A) of the segmented airway tree is binarized (B) by ImageJ software by assigning black pixel color for the airway tree and white pixel color for background. The box-counting algorithm places several grids of decreasing box size (C and D) over the ROI (ie, binarized image of the tracheobronchial tree to determine the fractal dimension).