Table II.
Patients with severe asthma (n = 48) | Patients with mild-to-moderate asthma (n = 17) | Healthy control subjects (n = 30) | Significance (P value) | |
---|---|---|---|---|
Inspiratory | ||||
Wall area/BSA (mm2/m2) | 18.2 (5.5) | 18.5 (3.7) | 18.7 (5.2) | .9 |
Lumen area/BSA (mm2/m2) | 11.3 (4.4) | 11.7 (3.0) | 13.7 (5.2) | .08 |
Total area/BSA (mm2/m2) | 29.5 (9.7) | 30.2 (6.4) | 32.3 (10.3) | .4 |
Wall area (mm2) | 34.8 (10.6) | 35.6 (8.0) | 36.1 (10.7) | .8 |
Lumen area (mm2) | 21.6 (8.4) | 22.6 (6.5) | 26 (10.3) | .06 |
Total area (mm2) | 56.4 (18.7) | 58.2 (14.2) | 62.6 (20.8) | .4 |
Length (mm) | 12.8 (2.7) | 11.8 (2.4) | 13.7 (4.4) | .2 |
Wall volume (mm3) | 437.6 (144.0) | 412.9 (88.5) | 496.3 (222.1) | .2 |
LV (mm3) | 272.3 (112.6) | 259.0 (53.3) | 366.4 (195.3) | .007*† |
Total volume (mm3) | 709.9 (252.4) | 672.0 (134.9) | 862.8 (414.6) | .05 |
Wall volume (%) | 62.4 (3.6) | 61.4 (2.9) | 58.5 (3.6) | <.0005*† |
Data are expressed as means (SDs).
BSA, Body surface area.
Intergroup comparisons
One-way ANOVA with the Tukey test to compare all pairs of columns: *P < .05, patients with severe asthma versus healthy control subjects; †P < .05, patients with mild-to-moderate asthma versus healthy control subjects; and ‡P < .05, patients with severe asthma versus patients with mild-to-moderate asthma.