. 2014 Mar;133(3):818–826.e4. doi: 10.1016/j.jaci.2013.09.038

Table II.

Statistical analysis of each cytokine per stimulation at all sites

	IFN-α2	IFN-γ	CXCL10	IL-12p70	IL-12p40	IL-6	IL-23	TNF-α	IL-1β	CXCL8	CCL3	CCL4	IL-10
Unstimulated
Global	.003	.0956	<.0001	.6486	.2065	.0024	<.0001	.0002	.3932	.0153	<.0001	.3424	.838
SAF vs BLG			NS				^∗	^∗			NS
SAF vs CND			^†				^‡	^‡			^‡
SAF vs ECD			NS				NS	NS			NS
BLG vs CND			^∗				NS	NS			^†
BLG vs ECD			NS				NS	NS			NS
CND vs ECD			^‡				^∗	^∗			^†
R848
Global	<.0001	<.0001	<.0001	<.0001	<.0001	<.0001	.0036	<.0001	<.0001	.0053	<.0001	<.0001	<.0001
SAF vs BLG	^†	^∗	^†	NS	NS	^‡		^‡	^∗		^‡	^†	^‡
SAF vs CND	^‡	^‡	^†	^‡	^‡	^∗		^‡	^‡		^†	^‡	^†
SAF vs ECD	^‡	^‡	^‡	^‡	^‡	^‡		^‡	^‡		^‡	^‡	^‡
BLG vs CND	NS	NS	NS	^∗	NS	NS		NS	NS		NS	NS	^‡
BLG vs ECD	NS	NS	NS	^‡	^∗	NS		NS	^∗		NS	NS	^†
CND vs ECD	NS	NS	NS	NS	NS	^†		NS	NS		^†	NS	NS
pIC
Global	<.0001	<.0001	<.0001	<.0001	<.0001	.1267	<.0001	<.0001	<.0001	.0041	<.0001	<.0001	.0031
SAF vs BLG	NS	NS	^†	NS	^‡		NS	NS	NS		NS	NS
SAF vs CND	^‡	^‡	^∗	^†	NS		^‡	^‡	^∗		^‡	^†
SAF vs ECD	^‡	^‡	^‡	^‡	^‡		NS	^‡	^†		^‡	^‡
BLG vs CND	^‡	^†	NS	NS	^‡		NS	NS	^‡		^†	NS
BLG vs ECD	^‡	^†	NS	^‡	NS		NS	^†	^‡		^‡	^‡
CND vs ECD	NS	NS	NS	NS	^‡		^‡	NS	NS		NS	^∗
LPS
Global	.0063	<.0001	<.0001	.1411	<.0001	<.0001	.0036	<.0001	<.0001	.0002	<.0001	<.0001	<.0001
SAF vs BLG		NS	^†		^‡	^‡		^∗	NS	^†	^‡	^†	^‡
SAF vs CND		^‡	^∗		^‡	^‡		^‡	^‡	NS	^‡	^†	^‡
SAF vs ECD		^†	^‡		^‡	^‡		^‡	^†	^†	^‡	^‡	^‡
BLG vs CND		^‡	NS		NS	NS		NS	^‡	NS	NS	NS	^‡
BLG vs ECD		NS	NS		NS	NS		NS	NS	NS	NS	NS	^‡
CND vs ECD		^∗	^∗		^†	NS		NS	^‡	NS	NS	NS	NS
PAM
Global	.0145	.6916	<.0001	.6243	<.0001	<.0001	.0001	<.0001	<.0001	<.0001	<.0001	<.0001	<.0001
SAF vs BLG			^†		^‡	^‡	NS	^‡	^†	^‡	^‡	^‡	^‡
SAF vs CND			NS		NS	NS	NS	NS	NS	NS	NS	NS	NS
SAF vs ECD			^‡		^‡	^‡	NS	^‡	^‡	^‡	^‡	^‡	^‡
BLG vs CND			^∗		NS	^∗	^‡	NS	NS	^‡	NS	NS	^‡
BLG vs ECD			NS		NS	NS	NS	NS	NS	NS	NS	NS	NS
CND vs ECD			^∗		NS	^‡	NS	^‡	^†	^‡	^‡	^‡	^‡
PGN
Global	.0174	.042	<.0001	.593	<.0001	<.0001	<.0001	<.0001	<.0001	<.0001	<.0001	.0044	<.0001
SAF vs BLG			NS		NS	^‡	NS	NS	NS	^‡	^†		^‡
SAF vs CND			NS		^‡	NS	NS	^‡	^†	NS	NS		^‡
SAF vs ECD			^∗		NS	^‡	^‡	NS	NS	^‡	^‡		^‡
BLG vs CND			^∗		^‡	^‡	^∗	NS	^‡	^‡	NS		NS
BLG vs ECD			NS		NS	NS	NS	NS	NS	NS	NS		^‡
CND vs ECD			^‡		^‡	^‡	^‡	^‡	^‡	^‡	NS		NS
MDP
Global	.005	.2408	<.0001	.7072	.9201	.0254	<.0001	<.0001	.0006	<.0001	.0007	<.0001	.0477
SAF vs BLG			^†				NS	^∗		^∗		NS
SAF vs CND			NS				^‡	^∗		NS		NS
SAF vs ECD			^†				NS	^‡		^†		^†
BLG vs CND			^†				NS	NS		^†		NS
BLG vs ECD			NS				NS	NS		NS		^†
CND vs ECD			^‡				^∗	^†		^‡		^‡

Note. The Kruskal-Wallis test for all 4 sites (global) was corrected for multiple comparisons by using the Bonferroni test (significant P value is P < .000595).

BLG, Belgium; CND, Canada; ECD, Ecuador; NS, not significant; SAF, South Africa.

^∗

Dunn’s post hoc test was applied to each site paring (statistical significance P value was <.05).

^†

Dunn’s post hoc test was applied to each site paring (statistical significance P value was <.01).

^‡

Dunn’s post hoc test was applied to each site paring (statistical significance P value was <.001).