Table 1.
Cytotoxicity values of RCS incubated 24 h at 37 °C in mouse myeloma B X63Ag5815 and caco2 cells. Cytotoxicity is determined by measurement of intracellular ATP content using the luciferin–luciferase reaction. Percent viability relative to control is calculated for the various RCS in each cell line and used to calculated IC50 values for growth inhibition.
| Compounds | Cytotoxic concentration IC50 (µM) |
|
|---|---|---|
| Lymphome B | Caco2 | |
| Acrolein | 3–6 | nd |
| Formaldehyde | 62.5–125 | 312–625 |
| Methylglyoxal | 250–500 | 625–1250 |
| 4-HNE | 5–10 | 10–15 |
| glyoxal | 625–1250 | nd |
| hexanal | >10 000 | nd |