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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Acta Biomater. 2013 Nov 25;10(3):1102–1111. doi: 10.1016/j.actbio.2013.11.013

Table 2.

Frequency of phenotypic marker immunohistochemical scores for NP cell-laden hydrogels of varying formulations.

N-cadherin

score 5% PEG 10% PEG 5% PEG 10% PEG 5% PEGa 10% PEG
0 μg/ml LM111 100 μg/ml LM111 500 μg/ml LM111
0 4 0 6 4 0 6
1 5 8 1 4 1 3
2 0 1 2 0 4 0
3 0 0 0 0 4 0
cytokeratin 8

score 5% PEG 10% PEG 5% PEGb 10% PEG 5% PEGb 10% PEG
0 μg/ml LM111 100 μg/ml LM111 500 μg/ml LM111

0 0 0 0 0 0 0
1 7 6 1 6 0 8
2 2 3 2 3 4 1
3 0 0 6 0 5 0
integrin α3

score 5% PEG 10% PEG 5% PEGc 10% PEG 5% PEGd 10% PEG
0 μg/ml LM111 100 μg/ml LM111 500 μg/ml LM111

0 1 0 0 0 0 0
1 5 7 0 4 1 4
2 0 2 1 3 4 5
3 0 0 8 2 4 0
a

Significantly different from hydrogels containing 5% PEG (0 or 100 μg/ml LM111) and formulations containing 10% PEG (0, 100 or 500 μg/ml) (p<0.004)

b

Significantly different from formulations containing 10% PEG (0, 100 or 500 μg/ml LM111) and hydrogels containing 5% PEG (0 μg/ml LM111) (p<0.004)

c

Significantly different from formulations containing 5% PEG (0 μg/ml LM111) and 10% PEG (0 or 500 μg/ml LM111) (p<0.004)

d

Significantly different from formulations containing 5% (0 μg/ml LM111) or 10% PEG (0 μg/ml LM111) (p<0.004)