Table 4.

Example 4 – LDR ¹²⁵I sources for permanent prostate BT.

Category	Typical level (%)	Assumptions
Source strength	3	PSDL traceable calibrations
Treatment planning	4	Reference data with the appropriate bin width
Medium dosimetric corrections	5	No consideration is given for calcifications or their composition in the patient
Inter-seed attenuation	4	An advanced dose calculation formalism may indicate source models and orientations cause the largest effects
Treatment delivery imaging	2	US QA performed according to AAPM TG-128
Target contouring uncertainty	2	Using CT or CT + T2 imaging
Anatomy changes between dose delivery and post-implant imaging	7⁎	Post-implant imaging using CT, with a scalar correction factor for edema correction
Total dosimetric uncertainty (k = 1)	11	For treatment delivered without excreted seeds

^⁎Estimated value based on expert discussion.