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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Mol Biol Rep. 2014 Jan 16;41(4):2067–2076. doi: 10.1007/s11033-014-3055-3

Fig. 1.

Fig. 1

CHN2 gene structure. a β3-chimaerin sequence (accession no: ADK47390.1). Red, N-terminal region encoded by exons 1a and 2a; green, SH2 domain; blue, C1 domain; yellow, Rac-GAP domain. b Structure of the CHN2 gene. The figure shows the exon arrangements leading to the different β-chimaerin isoforms. Red, exons that code for the β3-chimaerin N-terminal domain; green, exon 1b that is specific for the β2-chimaerin isoform. Yellow, β1-chimaerin’s exclusive 5′ sequence on exon 7b; gray, promoter sequences for the different isoforms. c Schematic view of the primers used to amplify full-length (primers 1 and 2) or N-terminal region of β3-chimaerin (primers 3 and 4). (Color figure online)