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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Support Care Cancer. 2013 Dec 21;22(5):1161–1169. doi: 10.1007/s00520-013-2068-0

Table 1.

Description and Sequence of Measures Administered at Each Visit

Test Test Score Associations with CIPN Afferent Nerve Fibers Tested

NCI Common Toxicity Criteria Increased
 Neuropathic Pain Scale Increased
 FACT&GOGntx Decreased

CPT Increased early (hyperesthesia) C (CPT 5 Hz)
Decreased later (hypoesthesia) Aδ (CPT 250 Hz)
Aβ (CPT 2000 Hz)

A. Thermal Detection Thresholds
  1. Cold Detection Threshold Increased temperature C
  2. Warm Detection Threshold Decreased temperature C
B. Pinprick Detection Decreased frequency
C. Mechanical Detection Threshold Increased monofilament gauge
D. Vibration Detection Decreased time to extinction
E. Grip Strength Decreased strength none
F. Deep Tendon Reflex Decreased reflex response