Skip to main content
. 2014 Mar;11(1):34–43. doi: 10.7497/j.issn.2095-3941.2014.01.003

Figure 2.

Figure 2

Graphical representation of pH-responsive MSNs with polyelectrolyte multilayers (A) and polyelectrolyte brushes (B). Release profiles of DOX from PEM-MENs (eight layers) in different pH media (C). DOX concentrations in plasma after DOX and DOX-loaded PEM-MSNs were injected intravenously through the vein for incremental time (D). Biodistribution of DOX in healthy SD rats at 2 h (E) and 24 h (F) after DOX and DOX-loaded PEM-MSNs at 2 mg/kg DOX equivalent were injected intravenously through the vein. *P<0.05 and **P<0.01 compared with free DOX group. (Figure 2C,D,E,F are adapted from Ref. 30 with permission from The Royal Society of Chemistry).