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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Transl Res. 2013 Oct 25;163(2):123–135. doi: 10.1016/j.trsl.2013.10.004

Table 1.

Embryonic/Larval Senescence Mutant Genes

Embryonic/larval SA-β-gal activity Gene GenBank Accession No.
Enhanced by loss-of-function 1) spinster homolog 1 (spns1) NM_153663
2) telomeric repeat binding factor a (terfa, terf2) NM_173243
3) clathrin interactor 1a (clint1a) NM_001003412
4) ATPase, H+ transporting, lysosomal, VO subunit c, a (atp6v0ca) NM_001105136
5) ATPase, H+ transporting, lysosomal, V1 subunit H (atp6v1h) NM_173270
6) polymerase (RNA) II (DNA directed) polypeptide D (polr2d) NM_001002317
7) polymerase (RNA) II (DNA directed) polypeptide G-like (polr2gl) NM_199669
8) smoothened homolog (smo) NM_131027
9) CCR4-NOT transcription complex, subunit 1 (cnot1) NM_001079951
10) structural maintenance of chromosomes 1A, like (smc1al) NM_212810
11) denticleless homolog (dtl) NM_173241

Suppressed by loss-of-function 1) eukaryotic translation initiation factor 3, subunit D (eif3d) NM_200016
2) ribosomal protein L11 (rpl11) NM_001002139
3) small nuclear ribonucleoprotein D1 polypeptide (snrpd1) NM_173252