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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: Biol Psychiatry. 2013 Oct 3;76(8):629–638. doi: 10.1016/j.biopsych.2013.08.016

Table 2.

Left hemisphere regions with significant differences in cortical thickness (mm) among children reared in institutions relative to community controls in the Bucharest Early Intervention Project (n=80)1,2

Cluster size Peak within
Cluster		 Approximate coordinates in
MNI space (x, y, z)
Brain Area (mm2) t x y z
1. Superior Parietal Cortex 307.0 −6.65 −15.2 −66.1 50.1
2. Superior Temporal Gyrus 567.7 −6.65 −52.8 −10.3 −0.7
3. Precentral Gyrus 179.4 −6.02 −35.2 −14.6 64.7
4. Superior Parietal Cortex 337.4 −5.91 −16.8 −52.4 60.5
5. Superior Parietal Cortex 168.0 −5.24 −16.7 −74.2 37.6
6. Posterior Cingulate 67.7 −5.10 −3.9 −26.7 26.6
7. Inferior Parietal Cortex 251.9 −4.22 −36.2 −63.8 40.9
8. Precuneus 158.6 −4.16 −8.2 −57.5 22.4
9. Paracentral 130.8 −4.04 −15.4 −41.5 62.8
10. Lateral Occipital 121.6 −4.00 −43.9 −81.0 1.7
11. Superior Parietal Cortex 53.9 −3.96 −28.6 −56.2 56.7
12. Superior Frontal Gyrus 179.4 −3.92 −9.1 62.9 17.4
13. Precuneus 121.1 −3.74 −9.9 −59.9 45.2
14. Fusiform Gyrus 55.6 −3.49 −33.9 −47.4 −11.9
15. Paracentral 15.5 −3.48 −8.5 −25.9 51.1
16. Precuneus 30.3 −3.35 −18.3 −41.2 45.5
17. Posterior Cingulate 25.7 −3.29 −10.4 −48.3 3.5
18. Middle Frontal Gyrus 79.5 −3.20 −19.7 61.2 4.0
19. Lateral Orbitofrontal Cortex 32.8 −3.18 −35.8 28.4 −7.2
20. Superior Temporal Gyrus 20.3 −3.15 −49.9 −29.0 −2.9
21. Precentral Gyrus 22.3 −3.03 −41.6 −7.3 53.3
22. Inferior Parietal Cortex 12.3 −2.99 −40.6 −60.9 42.9
23. Postcentral Gyrus 22.8 −2.93 −32.7 −35.9 55.6
24. Inferior Parietal Cortex 21.0 −2.91 −44.2 −72.6 25.9
25. Supramarginal Gyrus 17.8 −2.89 −47.5 −48.2 42.7
26. Insula 11.1 −2.89 −31.4 −29.7 13.4
27. Superior Temporal Sulcus 39.6 −2.87 −53.1 −51.5 3.4
28. Inferior Parietal Cortex 10.5 −2.85 −38.2 −84.3 14.5
29. Precuneus 6.5 −2.79 −13.0 −63.4 28.4
30. Supramarginal Gyrus 5.8 −2.76 −56.6 −29.4 18.9
31. Supramarginal Gyrus 0.4 −2.72 −44.5 −50.2 40.4
32. Superior Parietal Cortex 1.7 −2.72 −36.6 −48.6 51.5
33. Postcentral Gyrus 0.3 −2.71 −29.8 −32.3 68.2
34. Superior Frontal Gyrus 0.7 −2.71 −15.0 58.7 13.9
1

Analyses control for age, gender, total brain volume, and TR.

2

Significant group differences are shown at the p<.05 level, corrected for the false discovery rate (FDR). All significant group differences represent reduced cortical thickness in children reared in institutions relative to controls.