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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: Biol Psychiatry. 2013 Oct 3;76(8):629–638. doi: 10.1016/j.biopsych.2013.08.016

Table 3.

Right hemisphere regions with significant differences in cortical thickness (mm) among children reared in institutions relative to community controls in the Bucharest Early Intervention Project (n=80)1,2

Cluster size Peak within
Cluster		 Approximate coordinates in
MNI space (x, y, z)
Brain Area (mm2) t x y z
1. Middle Frontal Gyrus 197.7 −5.26 18.7 53.7 21.4
2. Inferior Parietal Cortex 353.6 −5.23 41.7 −55.9 41.1
3. Superior Frontal Gyrus 223.1 −5.10 20.6 23.4 55.1
4. Inferior Temporal Gyrus 136.5 −4.80 47.3 −45.1 −15.3
5. Supramarginal Gyrus 142.3 −4.76 40.7 −27.2 40.3
6. Superior Parietal Cortex 330.8 −4.71 26.7 −55.4 59.6
7. Frontal Pole 200.6 −4.47 10.0 64.0 −8.0
8. Precuneus 173.1 −4.33 16.2 −42.9 55.0
9. Superior Temporal Gyrus 73.0 −4.11 57.1 −4.8 −2.6
10. Lateral Orbitofrontal Cortex 62.9 −4.03 40.1 25.2 −13.7
11. Lateral Occipital Cortex 181.7 −4.02 40.6 −70.3 −1.9
12. Fusiform Gyrus 58.9 −3.83 29.3 −66.1 −13.8
13. Precuneus 22.0 −3.59 8.3 −54.7 52.1
14. Middle Frontal Gyrus 34.9 −3.51 36.9 26.8 43.4
15. Inferior Parietal Cortex 47.1 −3.49 42.2 −77.4 24.9
16. Insula 1.2 −3.29 31.0 13.6 −12.4
17. Inferior Parietal Cortex 24.1 −3.26 41.9 −71.0 35.0
18. Precuneus 27.6 −3.23 22.0 −67.3 15.1
19. Precuneus 26.6 −3.13 15.3 −69.8 39.0
20. Inferior Parietal Cortex 17.1 −3.11 51.7 −56.1 13.2
21. Lingual Gyrus 32.6 −3.11 15.7 −73.0 −5.8
22. Superior Parietal Cortex 26.0 −3.09 18.4 −66.3 46.8
23. Supramarginal Gyrus 8.9 −3.05 55.5 −34.5 35.2
24. Precuneus 19.9 −2.94 10.7 −66.1 34.9
25. Superior Temporal Sulcus 3.5 −2.93 49.8 −41.8 14.3
26. Superior Parietal Cortex 5.9 −2.92 24.1 −84.3 30.7
27. Insula 0.3 −2.92 29.6 13.4 −13.7
1

Analyses control for age, gender, total brain volume, and TR.

2

Significant group differences are shown at the p<.05 level, corrected for the false discovery rate (FDR). All significant group differences represent reduced cortical thickness in children reared in institutions relative to controls.