Table 3.

Predictive Value of CSF α-Syn in Cognitive Decline

Test	Baseline: phase 1			Final: phase 2
	Coefficient	SE	P value	Coefficient	SE	P value
SDMT	−0.0445	0.0737	0.546	−0.1071	0.0707	0.131
SRT-Total Recall∗	−0.1301	0.0950	0.183	−0.1240	0.0590	0.037
SRT-Delayed Recall	−0.0151	0.0276	0.587	−0.0516	0.0166	0.002
New Dot Test	−0.0062	0.0154	0.686	−0.0326	0.0103	0.002

See Table 2 for the phase 2 results, with or without controlling for mean LEDD.

Bold indicates significance at the P < 0.05 level.

^∗Controlling for age, sex, education, baseline UPDRS, baseline test score, length of exposure to deprenyl, and exposure to tocopherol.