Table 2.

Recognition of fewer epitopes in active disease than in latently infected subjects.

Subjects (no. tested)	Peptides from	Frequency (%) of respondersa, no. of test peptides (p)
From Londonb	Acr	1–3 p	4–6 p	>6 p
Healthy PPD+ skin test (25)		24	52	24
Active TB (38)		52	30	18
From Bangkokc	GroES	1–4 p	5–10 p	>10 p
Healthy family contacts (12)		<1	58	42
Tuberculoid leprosy (18)		33	56	11

^aBlood mononuclear cells of responders had at least threefold elevated ³H-thymidine uptake in cultures containing the test peptide over medium alone.Data from:

^bFriscia et al. (32);

^cChua-Intra et al. (24).