Table 1.
Non-obese |
Obese |
p | |||
---|---|---|---|---|---|
Non-OSA (group 1) | OSA (group 2) | Non-OSA (group 3) | OSA (group 4) | ||
(n = 26) | (n = 30) | (n = 20) | (n = 38) | ||
Age (years) | 9.1 ± 3.1 | 9.9 ± 4.3 | 11.4 ± 3.2 | 11.2 ± 3.2 | 0.056 |
Male gender, n (%) | 19 (73.1) | 20 (66.7) | 16 (80.0) | 22 (57.9) | 0.334 |
Weight (kg)c | 29.3 ± 10.1 | 34.9 ± 17.8 | 63.7 ± 16.3 | 61.5 ± 21.4 | <0.001 |
Height (m)b | 1.32 ± 0.16 | 1.34 ± 0.24 | 1.51 ± 0.14 | 1.47 ± 0.15 | <0.001 |
BMI z-scorec | −0.004 ± 0.926 | 0.297 ± 1.051 | 2.209 ± 0.313 | 2.309 ± 0.472 | <0.001 |
SBP (mmHg)c | 101 ± 12 | 111 ± 17 | 121 ± 13 | 123 ± 16 | <0.001 |
DBP (mmHg) | 61 ± 9 | 65 ± 8 | 68 ± 6 | 70 ± 9 | 0.002 |
OAI/ha,d | 0 (0–0) | 1.7 (0.5–7.1) | 0 (0–0.1) | 1.0 (0.2–4.6) | <0.001 |
OAHI/ha,d | 0.2 (0–0.5) | 9.4 (4.2–19.8) | 0.2 (0.1–0.5) | 4.5 (2.0–14.2) | <0.001 |
Arousal index/ha | 5.7 (3.9–9.9) | 8.9 (6.6–14.5) | 5.3 (4.0–7.8) | 6.0 (4.4–13.6) | 0.007 |
ANP (fmol/ml)b | 2292 ± 948 | 2026 ± 656 | 1467 ± 655 | 1660 ± 658 | <0.001 |
BNP (pmol/l) | 3.1 (1.6–7.6) | 3.7 (1.6–9.6) | 1.4 (0.3–5.3) | 2.8 (0.7–5.4) | 0.067 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; OAI, obstructive apnea index; OAHI, obstructive apnea–hypopnea index; ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide.
Data were presented as mean ± SD, median (IQR), and number (percentage) for parametric, non-parametric, and categorical data, respectively.
p values were obtained from ANOVA, Kruskal–Wallis test, and Chi-square test table for parametric, non-parametric, and categorical data, respectively.
Post hoc analyses, Tukey HSD, or Games–Howell method for the parametric variables and Mann–Whitney U test with adjusted p values (significant at p < 0.008) for non-parametric variables.
aSignificant difference between group 1 and 2.
bSignificant difference between group 1 and 3.
cSignificant difference between group 2 and 4.
dSignificant difference between group 3 and 4.