Table 2.
All | Detected by EBGM | Not detected by EBGM | p | ||||
---|---|---|---|---|---|---|---|
N | PRR | N | PRR | N | PRR | ||
Cisplatin | 479 | 8.03 ± 11.29 | 175 | 12.90 ± 16.73 | 304 | 5.23 ± 4.36 | < 0.001 |
Carboplatin | 409 | 6.80 ± 8.32 | 144 | 10.57 ± 12.25 | 265 | 4.76 ± 3.69 | < 0.001 |
Oxaliplatin | 410 | 7.72 ± 11.47 | 150 | 11.69 ± 17.16 | 260 | 5.43 ± 4.90 | < 0.001 |
Colistin | 71 | 29.30 ± 83.82 | 23 | 77.31 ± 136.92 | 48 | 6.29 ± 4.66 | < 0.001 |
5-Fluorouracil | 461 | 7.52 ± 10.03 | 161 | 11.61 ± 14.90 | 300 | 5.33 ± 4.72 | < 0.001 |
Capecitabine | 411 | 8.09 ± 13.06 | 146 | 12.07 ± 20.26 | 265 | 5.90 ± 5.09 | < 0.001 |
Pravastatin | 218 | 4.70 ± 4.26 | 19 | 10.48 ± 8.61 | 199 | 4.15 ± 3.11 | < 0.001 |
Simvastatin | 192 | 4.50 ± 4.81 | 30 | 8.99 ± 10.33 | 162 | 3.66 ± 1.94 | < 0.001 |
Atorvastatin | 284 | 3.76 ± 1.93 | 55 | 4.41 ± 1.99 | 229 | 3.61 ± 1.89 | < 0.001 |
Rosuvastatin | 227 | 5.20 ± 5.77 | 63 | 8.50 ± 9.37 | 164 | 3.94 ± 2.65 | < 0.001 |
Tigecycline | 91 | 37.88 ± 114.30 | 44 | 72.09 ± 158.16 | 47 | 5.85 ± 3.57 | < 0.001 |
Omeprazole | 213 | 4.69 ± 5.05 | 14 | 12.29 ± 15.28 | 199 | 4.16 ± 2.77 | 0.003 |
Esomeprazole | 194 | 4.65 ± 3.83 | 17 | 7.19 ± 9.50 | 177 | 4.41 ± 2.68 | 0.513 |
Warfarin | 331 | 5.28 ± 4.95 | 110 | 7.46 ± 7.38 | 221 | 4.19 ± 2.47 | < 0.001 |
Aspirin | 348 | 5.56 ± 4.93 | 100 | 8.05 ± 7.39 | 248 | 4.56 ± 2.96 | < 0.001 |
Clopidogrel | 366 | 4.85 ± 3.79 | 104 | 6.77 ± 5.44 | 262 | 4.08 ± 2.52 | < 0.001 |
PRR-based signals were divided into 2 groups based on whether adverse events were also detected by the EBGM method.