Table 1.
HCMV complete genome sequences available on NCBI GenBank, listed in order of submission date.
| GenBank accession | Strain name | Clinical source | Passage history | Ref. | Submission date |
|---|---|---|---|---|---|
| X17403 | AD169 | Adenoids of a 7-year old girl | Passaged extensively in human fibroblasts | [12] | December 6, 1989 |
| BK00039’ | AD169 varUK | Adenoids of a 7-year old girl | Passaged extensively in human fibroblasts | [40] | May 1, 2002 |
| NC_006273*GU179001 | Merlin | Urine from a congenitally infected infant | Passaged 3 times in human fibroblasts | [25] | September 27, 2002 |
| AY315197 | Towne varS | Urine of a 2-month-old infant with microcephaly and hepatosplenomegaly | Passaged extensively in human fibroblasts | [30] | June 6, 2003 |
| AC146851 | Towne-BAC | Urine of a 2-month-old infant with microcephaly and hepatosplenomegaly | BAC clone from a plaque purified Towne derivative (varS) | [39] | October 14, 2003 |
| AC146904 | PH-BAC | Transplant patient with HCMV disease | BAC clone from isolate PH (passaged less than 12 times) | [39] | October 21, 2003 |
| AC146905 | Toledo-BAC | Urine from a congenitally infected infant | BAC clone from a plaque purified Toledo derivative | [39] | October 21, 2013 |
| AC146906 | TR-BAC | AIDS patient with CMV retinitis | BAC clone from isolate TR | [39] | October 21, 2013 |
| AC146907 | FIX-BAC | Cervical secretions of a pregnant woman with a primary HCMV infection | BAC clone from isolate VR1814 | [39] | October 21, 2013 |
| AC146999 | AD169-BAC | Adenoids of a 7-year old girl | BAC clone from a plaque purified AD169 derivative (varATCC) | [39] | October 31, 2013 |
| EF999921 | TB40/E clone TB40-BAC4 | Throat wash of a bone marrow transplant recipient | BAC clone from TB40/E passaged 5 times in human fibroblasts and 22 times in human endothelial cells | [41] | June 25, 2007 |
| FJ527563 | AD169 varUC | Adenoids of a 7-year old girl | Passaged extensively in human fibroblasts | [20] | December 1, 2008 |
| FJ616285 | Towne varL | Urine of a 2-month-old infant with microcephaly and hepatosplenomegaly | Passaged extensively in human fibroblasts | [20] | January 9, 2009 |
| GQ221973 | HAN13 | Bronchoalveolar lavage | Passaged 3 times in human fibroblasts | [42] | May 28, 2009 |
| GQ221974 | 3157 | Urine from a congenitally infected infant | Passaged 3 times in human fibroblasts | [42] | May 28, 2009 |
| GQ221975 | JP | Post mortem prostate tissue from an AIDS patient | Unpassaged | [42] | May 28, 2009 |
| GQ396662 | HAN38 | Bronchoalveolar lavage | Passaged 2 times in human fibroblasts | [42] | July 17, 2009 |
| GQ396663 | HAN20 | Bronchoalveolar lavage | Passaged 2 times in human fibroblasts | [42] | July 17, 2009 |
| GQ466044 | 3301 | Urine from a congenitally infected infant | Unpassaged | [42] | August 7, 2009 |
| GU179288 | U8 | Urine from a congenitally infected infant | Unpassaged | [42] | November 5, 2009 |
| GU179289 | VR1814 | Cervical secretions of a pregnant woman with a primary HCMV infection | Unpassaged | [42] | November 5, 2009 |
| GU179290 | U11 | Urine from a congenitally infected infant | Unpassaged | [42] | November 5, 2009 |
| GU179291 | AF1 | Amniotic fluid | Unpassaged | [42] | November 5, 2009 |
| GU937742 | Toledo | Urine from a congenitally infected infant | Passaged several times in human fibroblasts | [25] | February 26, 2010 |
| HQ380895 | JHC | Blood from a bone marrow transplant patient | Plaque purified and passaged 3 times in human fibroblasts | [43] | October 7, 2010 |
| JX512197 | 6397 | Urine from a congenitally infected infant | Passaged 3 times in human fibroblasts | - | August 21, 2012 |
| JX512198 | Davis | Liver biopsy from a congenitally infected infant | Passaged many times in human fibroblasts | - | August 21, 2012 |
| JX512199 | HAN1 | Bronchoalveolar lavage | No information | - | August 21, 2012 |
| JX512200 | HAN2 | Bronchoalveolar lavage | Passaged 3 times in human fibroblasts | - | August 21, 2012 |
| JX512201 | HAN3 | Bronchoalveolar lavage | Passaged 3 times in human fibroblasts | - | August 21, 2012 |
| JX512202 | HAN8 | Bronchoalveolar lavage | Passaged 3 times in human fibroblasts | - | August 21, 2012 |
| JX512203 | HAN12 | Bronchoalveolar lavage | Passaged 3 times in human fibroblasts | - | August 21, 2012 |
| JX512204 | HAN16 | Urine from an infant | Passaged 2 times in human fibroblasts | - | August 21, 2012 |
| JX512205 | HAN19 | Bronchoalveolar lavage | Passaged 2 times in human fibroblasts | - | August 21, 2012 |
| JX512206 | HAN22 | Bronchoalveolar lavage | Passaged 2 times in human fibroblasts | - | August 21, 2012 |
| JX512207 | HAN28 | Bronchoalveolar lavage | Passaged 3 times in human fibroblasts | - | August 21, 2012 |
| JX512208 | HAN31 | Bronchoalveolar lavage | Passaged 2 times in human fibroblasts | - | August 21, 2012 |
| KC519319 | BE/9/2010 | Urine from an infant | Passaged 2 times in human fibroblasts | - | January 23, 2013 |
| KC519320 | BE/10/2010 | Urine from a congenitally infected infant | Passaged 2 times in human fibroblasts | - | January 23, 2013 |
| KC519321 | BE/11/2010 | Urine from an infant | Passaged 2 times in human fibroblasts | - | January 23, 2013 |
| KC519322 | BE/21/2010 | Urine from a pulmonary transplant recipient | Unpassaged | - | January 23, 2013 |
| KC519323 | BE/27/2010 | Urine from a renal transplant recipient | Passaged 4 times in human fibroblasts | - | January 23, 2013 |
| KF021605 | TR | Vitreous humor from eye of HIV-positive male | Passaged several times in human fibroblasts | [44] | May 9, 2013 |
| KF297339 | TB40/E clone Lisa | Throat wash of a bone marrow transplant recipient | Generated on human fibroblasts by passaging strain TB40/E once, plaque purifying 3 times and passaging once more | [45] | June 26, 2013 |
°NCBI GenBank release file 199.0; search performed on 15 January 2014; patent sequences, transgenic strains, and incomplete sequences were not included; *NCBI Reference Sequence (RefSeq); “Update from AD169 entry X17403 by the addition of the 929 bp missing region, encompassing UL42 and UL43, and the correction of sequencing errors.