Table 2.
Overview of studies on the HCMV genome making use of NGS technology, ranked in chronological order.
| First author | Title | Journal | NGS technology | Ref. | Publication date |
|---|---|---|---|---|---|
| Bradley et al. | High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169. | J. Gen. Virol. | IGA° | [20] | June 24, 2009 |
| Cunningham et al. | Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens. | J. Gen. Virol. | IGA° | [42] | November 11, 2009 |
| Görzer et al. | Deep sequencing reveals highly complex dynamics of human cytomegalovirus genotypes in transplant patients over time. | J. Virol. | GSF* | [77] | May 12, 2010 |
| Stanton et al. | Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication. | J. Clin. Invest. | IGA° | [35] | August 2, 2010 |
| Görzer et al. | The impact of PCR-generated recombination on diversity estimation of mixed viral populations by deep sequencing. | J. Virol. Methods | GSF* | [78] | August 4, 2010 |
| Jung et al. | Full genome sequencing and analysis of human cytomegalovirus strain JHC isolated from a Korean patient. | Virus Res. | GSF* | [43] | January 19, 2011 |
| Renzette et al. | Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants. | PLoS Pathog. | IGA° | [79] | May 19, 2011 |
| James et al. | Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase. | Antimicrob. Agents Chemother. | IGA° | [80] | July 25, 2011 |
| Stark et al. | High-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection. | J. Virol. | IGA° | [81] | October 19, 2011 |
| Gatherer et al. | High-resolution human cytomegalovirus transcriptome. | Proc. Natl. Acad. Sci. U. S. A. | IGA° | [82] | November 22, 2011 |
| Bhattacharjee et al. | Genetic analysis of cytomegalovirus in malignant gliomas. | J. Virol. | IGA° | [83] | April 11, 2012 |
| Meshesha et al. | The microRNA Transcriptome of Human Cytomegalovirus (HCMV). | Open Virol. J. | IGA° | [84] | April 11, 2012 |
| Stern-Ginossar et al. | Decoding human cytomegalovirus. | Science | IGA°, HiSeq^ | [85] | November 23, 2012 |
| Rossetto et al. | Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells. | PLoS Pathog. | MiSeq’ | [86] | May 23, 2013 |
| Sahoo et al. | Detection of cytomegalovirus drug resistance mutations by next-generation sequencing. | J. Clin. Microbiol. | GSJ” | [87] | August 28, 2013 |
| Renzette et al. | Rapid intrahost evolution of human cytomegalovirus is shaped by demography and positive selection. | PLoS Genet. | IGA° | [88] | September 26, 2013 |
| Brechtel et al. | Complete Genome Sequence of a Cytomegalovirus Towne-BAC (Bacterial Artificial Chromosome) Isolate Maintained in Escherichia coli for 10 Years and Then Serially Passaged in Human Fibroblasts. | Genome Announc. | MiSeq’ | [75] | September 26, 2013 |
| Brechtel et al. | Complete Genome Sequence of a UL96 Mutant Cytomegalovirus Towne-BAC (Bacterial Artificial Chromosome) Isolate Passaged in Fibroblasts To Allow Accumulation of Compensatory Mutations. | Genome Announc. | MiSeq’ | [76] | October 24, 2013 |
° Genome Analyzer (Illumina); * 454 GS FLX (Roche); ^ HiSeq (Illumina); ‘ MiSeq (Illumina); “ 454 GS Junior (Roche).