Table 1.
Virus | pre-miRs | mature miRs | miRNAs with proposed function | Target | Proposed function |
---|---|---|---|---|---|
MDV-1 | 14 | 26 | mdv1-mir-M3 | Smad2 | Anti-apoptotic [31]. |
mdv1-mir-M4-5p | Pu.1, CEBPβ, HIVEP2, BCL2L13, PDCD6, GPM6B, RREB1, c-Myb, MAP3K7IP2 | Mimics cellular mir-155 [32,33,34]. | |||
mdv1-mir-M4-3p | UL28 | Prevent lytic replication/promote latency [33] | |||
UL32 | Prevent lytic replication/promote latency [33] | ||||
mdv1-mir-M7-5p | ICP4 and ICP27 | Establish and/or maintain latency [ 35] | |||
mdv1-mir-M2 | R-LORF8 | Lymphocyte growth [34] | |||
MDV-2 | 18 | 36 | mdv2-mir-M29 | R-LORF2 | Lymphocyte growth [34] |
HVT | 17 | 28 | |||
ILTV | 7 | 10 | iltv-mir-I5 | ICP4 | Establish and/or maintain latency [36] |
DEV | 24 | 33 | |||
ALV-J | 1 | 2 | E(XSR)miR | Potential role in oncogenesis |