Skip to main content
. 2014 Mar 21;6(3):1379–1394. doi: 10.3390/v6031379

Table 1.

Avian virus encoded miRNAs and proposed functions highlighted in this review.

Virus pre-miRs mature miRs miRNAs with proposed function Target Proposed function
MDV-1 14 26 mdv1-mir-M3 Smad2 Anti-apoptotic [31].
mdv1-mir-M4-5p Pu.1, CEBPβ, HIVEP2, BCL2L13, PDCD6, GPM6B, RREB1, c-Myb, MAP3K7IP2 Mimics cellular mir-155 [32,33,34].
mdv1-mir-M4-3p UL28 Prevent lytic replication/promote latency [33]
UL32 Prevent lytic replication/promote latency [33]
mdv1-mir-M7-5p ICP4 and ICP27 Establish and/or maintain latency [ 35]
mdv1-mir-M2 R-LORF8 Lymphocyte growth [34]
mdv1-mir-M3
mdv1-mir-M4
mdv1-mir-M12
MDV-2 18 36 mdv2-mir-M29 R-LORF2 Lymphocyte growth [34]
mdv2-mir-M28
mdv2-mir-M27
mdv2-mir-M26
mdv2-mir-M25
mdv2-mir-M24
HVT 17 28
ILTV 7 10 iltv-mir-I5 ICP4 Establish and/or maintain latency [36]
DEV 24 33
ALV-J 1 2 E(XSR)miR Potential role in oncogenesis