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. Author manuscript; available in PMC: 2015 Jan 7.
Published in final edited form as: Radiat Res. 2014 Jan 7;181(1):76–89. doi: 10.1667/RR13405.1

TABLE 3.

Radioresistance of Hematopoietic Colony Forming Progenitor Cells from Fresh Fancd2 −/− Mouse Bone Marrow

Fancd2 CFU-GM BFU-E CFU-GEMM
bone marrow D0 ñ D0 ñ D0 ñ
Fancd2−/− 1.62 ± 0.09
P1 = 0.049a
P2 = 0.007b 		3.02 ± 0.10
P1 = 0.001a
P2 = 0.0001b 		1.67 ± 0.18 1.4 ± 0.2 2.46 ± 0.25 1.02 ± 0.02
Fancd2+/− 2.23 ± 0.07 1.24 ± 0.03 2.15 ± 0.11 1.64 ± 0.36 2.35 ± 0.18 1.00 ± 0.00
Fancd2+/+ 2.44 ± 0.27 1.35 ± 0.18 2.11 ± 0.43 1.66 ± 0.33 2.02 ± 0.11 2.11 ± 0.60

Notes. Whole-femur bone marrow from Fancd2+/+, Fancd2+/− and Fancd2−/− mice were irradiated in single cell suspension with doses between 0–8 Gy as described in the Methods section. CFU-GM, BFU-E and CFU-GEMM were scored when colonies reached ≥50 cells in days 10–13. Results are the mean ± SEM of three separate experiments.

a

P1 = comparison between +/+ group and −/− group.

b

P2 = comparison between heterozygote +/− group and −/− group.