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. Author manuscript; available in PMC: 2014 Aug 16.
Published in final edited form as: Circ Res. 2013 Jul 1;113(5):562–570. doi: 10.1161/CIRCRESAHA.113.301510

Figure 5. IKK2 deficiency reduces vascular contractile responses.

Figure 5

A, average mean arterial pressures, measured 24 hrs/day for 4 days by telemetry, in TNFR1−/− IKK2smKo (n=8) and their littermate TNFR1−/− controls (n=6).*P<0.05 vs. TNFR1−/−; two way ANOVA. B-E, acute increases in mean arterial pressure (ΔMAP) of TNFR1−/− IKK2smKo and their littermate TNFR1−/− controls in response to phenylephrine (PE, 10 µg/kg, B), thromboxane A2 agonist (TXA, 30 µg/kg, C), angiotensin II (AngII, 0.3 µg/kg, D), and nitroprusside sodium (NPS, 32 µg/kg, E). n=6/group. *P<0.05 v.s. TNFR1−/−; student t-test.