Table 3.
Patterns of Nerve Enlargement in CMT-1 and Acquired Demyelinating Polyneuropathies
Diagnosis (n= (%)) | ||||
---|---|---|---|---|
Pattern of Nerve Enlargement | CMT-1 n=35 | CIDP n=55 | GBS n=21 | MMN n=17 |
None | 0 (0%) | 11 (20%) | 10 (48%) | 6 (35%) |
Mild-Type 1 | 2 (6%) | 13 (24%) | 8 (38%) | 7 (41%) |
Regional- Type 2 | 2 (6%) | 11 (20%) | 2 (10%) | 4 (24%) |
Diffuse-Type 3 | 31 (89%) | 20 (37%)* | 1 (5%)* | 0 (0%)* |
p<0.001 compared to CMT-1
Nerves are more likely to be very enlarged on average and at multiple sites in CMT-1 than CIDP, GBS, and MMN. Average NSI in each demyelinating neuropathy group was larger (p≤0.05) than in controls.