Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2014 Mar 31.

Published in final edited form as: J Neurochem. 2012 Jun 13;122(3):619–627. doi: 10.1111/j.1471-4159.2012.07784.x

Phasic glutamate release area for the duration of the 5 minute restraint stress, which occurred 60 minutes following a single subcutaneous injection (2 ml/kg) of either vehicle (n=6), LY354740 (10 mg/kg; n=8 (day 3), n=6 (day 5)), (+)-TFMPIP (1 mg/kg, n=6), or (+)-TFMPIP (17.8 mg/kg, n=6) on day 3 (A) and 5 (B) post-implantation. There was no change in stress response in the LY354740 treated rats. However, both doses of the (+)-TFMPIP drug produced significant decreases in the stress response on days 3 and 5. *p<0.05, **p<0.01 based on a one-way ANOVA with a Tukey’s post-hoc test.

Phasic glutamate release area for the duration of the 5 minute restraint stress, which occurred 60 minutes following a single subcutaneous injection (2 ml/kg) of either vehicle (n=6), LY354740 (10 mg/kg; n=8 (day 3), n=6 (day 5)), (+)-TFMPIP (1 mg/kg, n=6), or (+)-TFMPIP (17.8 mg/kg, n=6) on day 3 (A) and 5 (B) post-implantation. There was no change in stress response in the LY354740 treated rats. However, both doses of the (+)-TFMPIP drug produced significant decreases in the stress response on days 3 and 5. *p<0.05, **p<0.01 based on a one-way ANOVA with a Tukey’s post-hoc test.